Prior work

Modalities lean teams ask us to pressure-test.

Anonymized accounts of the investment questions that show up under a live deadline—what claims get tested, what triggers surface, and where the sprint boundary sits. Not fictional sample memos. Not named case studies.

Accounts are intentionally non-specific. Client identities, confidential findings, and investment outcomes are omitted. These describe types of diligence pressure-tests performed — not case studies with results.

Cell therapy
Extracellular vesicles
Monoclonal antibodies
Nucleotide therapeutics
Diagnostics
HCTP-regulated tissue technologies

Non-specific work account

Cell therapy

Early investment and partnership reviews of autologous and allogeneic cell programs, including platform-plus-pipeline structures where the thesis mixed product claims with manufacturing and control-strategy readiness.

Decision pressure

Term-sheet timing forced a sharp cut between what was demonstrated in limited clinical/process packages versus what still depended on unproven scale, release, or comparability assumptions.

Boundary

Did not substitute for formal CMC, regulatory, or clinical-statistical opinions; flagged when those were required.

Claims typically pressure-tested

  • Whether potency and product identity claims were decision-grade for the proposed next study
  • Whether CMC / process control risk would consume the raise before a claim-resolving readout
  • Whether comparator and failed-analogue programs actually supported the differentiation story

Example decision triggers surfaced

  • Potency assay or release strategy not yet tied to the clinical claim
  • Comparability after process change left as narrative rather than a plan
  • Use of proceeds not mapped to the must-be-true manufacturing gates

Browse the decision catalogue →

Live deal in one of these domains—and a thin science bench?

Start with a non-confidential fit request. Conflict check and NDA come before any data-room access.