How to make a therapeutic mechanism easier for investors to understand

A mechanism narrative is not a literature review. It is a guided tour: what the intervention does, where it acts, what evidence constrains belief, and what would change your mind if the next experiment fails.

Good mechanism pages use consistent entity naming, explicit scope boundaries (species, model class, patient context), and a clear separation between validated facts and forward projections. They also surface the comparator frame early, because most readers implicitly ask “compared to what?” long before you want them to.

Finally, the page should be easy to share. If a partner can forward one URL and the recipient can orient in minutes, you have reduced coordination cost—which is a practical definition of legibility.